Substance

ID:184086

Ro 25-6981 hydrochloride hydrate

Names and Identifiers
IUPAC name
4-[(1R,2S)-2-[(4-benzylpiperidin-1-yl)methyl]-1-hydroxypropyl]phenol hydrate hydrochloride
Synonyms
[R-(R*,S*)]-α-(4-Hydroxyphenyl)-β-methyl-4-(phenylmethyl)-1-piperidinepropanol hydrochloride hydrateRo 25-6981 hydrochloride hydrate
IUPAC Traditional name
4-[(1R,2S)-2-[(4-benzylpiperidin-1-yl)methyl]-1-hydroxypropyl]phenol hydrate hydrochloride
Registration numbers
PubChem SID
Properties
Product Information
Purity
≥98% (HPLC)
Safety Information
European Hazard Symbols
Irritant Irritant (Xi)
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
GHS Pictograms
GHS07
Acute toxicity (oral, dermal, inhalation), category 4
Skin irritation, category 2
Eye irritation, category 2
Skin sensitisation, category 1
Specific Target Organ Toxicity – Single exposure, category 3
Risk Statements
36/37/38
GHS Signal Word
Warning
GHS Hazard statements
H315-H319-H335
GHS Precautionary statements
P261-P305+P351+P338
Safety Statements
26-36
Storage Condition
desiccated
German water hazard class
3
Pharmacology Properties
Gene Information
human ... GRIN2B(2904)
Physical Property
Apperance
white powder
Solubility
DMSO: >20 mg/mL
Molecule Details
Biochem/physiol Actions
Potent and selective antagonist of NMDA glutamate receptors containing the NR2B subunit.
Molecular Spectra
No Data Available
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References
No Data Available
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