Substance
ID:1840501
Names and Identifiers
IUPAC name
({[(2R)-1-(6-amino-9H-purin-9-yl)propan-2-yl]oxy}methyl)phosphonic acid
IUPAC Traditional name
tenofovir
Synonyms
tenofovir (anhydrous)(R)-PMPAanh. tenofoviranhydrous tenofovirtenofovir (anh.)
International Nonproprietary Name (INN)
tenofovir
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CHEMBL
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Protein Data Bank
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CHEBI ID
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Properties
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Molecule Details
A member of the class of phosphonic acids that is methylphosphonic acid in which one of the methyl hydrogens is replaced by a [(2R)-1-(6-amino-9H-purin-9-yl)propan-2-yl]oxy group. An inhibitor of HIV-1 reverse transcriptase, the bis(isopropyloxycarbonyloxymethyl) ester (disoproxil ester) prodrug is used as the fumaric acid salt in combination therapy for the treatment of HIV infection.
Molecular Spectra
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References
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