Substance
ID:183997
Names and Identifiers
Synonyms
DFMO hydrochloride hydrateEflornithine hydrochloride hydrateDL-α-Difluoromethylornithine hydrochloride hydrate2-(Difluoromethyl)ornithine hydrochloride hydrate
IUPAC Traditional name
vaniqa hydrate hydrochloride
IUPAC name
2,5-diamino-2-(difluoromethyl)pentanoic acid hydrate hydrochloride
Properties
Physical Property
Solubility
DMSO: >10 mg/mL
H2O: >10 mg/mL
Apperance
white solid
Product Information
Purity
≥97% (NMR)
Safety Information
Personal Protective Equipment
Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
German water hazard class
3
Pharmacology Properties
Gene Information
human ... ODC1(4953)
Molecule Details
Biochem/physiol Actions
Difluoromethylornithine (Eflornithine) inhibits polyamine biosynthesis by the selective, irreversible inhibition of ornithine decarboxylase (ODC). A chemoprotective agent that blocks angiogenesis.
Difluoromethylornithine (Eflornithine) inhibits polyamine biosynthesis by the selective, irreversible inhibition of ornithine decarboxylase (ODC). A chemoprotective agent that blocks angiogenesis.
Molecular Spectra
No Data Available
Click here to submit data
References
No Data Available
Click here to submit data