Substance

ID:183945

Names and Identifiers
Synonyms
Carboplatincis-Diammine(1,1-cyclobutanedicarboxylato) platinum
IUPAC name
6,8-dioxa-7-platinaspiro[3.5]nonane-5,9-dione diamine
IUPAC Traditional name
6,8-dioxa-7-platinaspiro[3.5]nonane-5,9-dione diamine
Registration numbers
CAS Number
41575-94-4
MDL Number
MFCD00070464
EC Number
255-446-0
PubChem SID
24278303
Properties
Safety Information
Personal Protective Equipment
Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
German water hazard class
3
Safety Statements
53-22-26-36/37/39-45
GHS Hazard statements
H302+H312+H332-H317-H334-H360
GHS Pictograms
GHS08
Respiratory sensitization, category 1
Germ cell mutagenicity, categories 1A,1B,2
Carcinogenicity, categories 1A,1B,2
Reproductive toxicity, categories 1A,1B,2
Specific Target Organ Toxicity – Single exposure, categories 1,2
Specific Target Organ Toxicity – Repeated exposure, categories 1,2
Aspiration Hazard, category 1
GHS07
Acute toxicity (oral, dermal, inhalation), category 4
Skin irritation, category 2
Eye irritation, category 2
Skin sensitisation, category 1
Specific Target Organ Toxicity – Single exposure, category 3
GHS Signal Word
Danger
Risk Statements
46-61-20/21/22-42/43
GHS Precautionary statements
P201-P261-P280-P308+P313
RTECS
TP2300000
European Hazard Symbols
Toxic Toxic (T)
Molecule Details
Biochem/physiol Actions
Carboplatin is a platinum-based antineoplastic drug that damages DNA by forming intrastrand cross-links with neighboring guanine residues. Tumors acquire resistance to these drugs through the loss of DNA-mismatch repair (MMR) activity and the resultant decrease in the induction of programmed cell death.
Molecular Spectra
No Data Available
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References
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