Substance
ID:183638
Names and Identifiers
IUPAC Traditional name
triamcinolone
IUPAC name
(1R,2S,10S,11S,13R,14S,15S,17S)-1-fluoro-13,14,17-trihydroxy-14-(2-hydroxyacetyl)-2,15-dimethyltetracyclo[8.7.0.02,7.011,15]heptadeca-3,6-dien-5-one
Synonyms
9α-Fluoro-11β,16α,17,21-tetrahydroxy-1,4-pregnadiene-3,20-dione9α-Fluoro-11β,16α,17,21-tetrahydroxypregna-1,4-diene-3,20-dioneTriamcinoloneFluoxyprednisolone
Properties
Pharmacology Properties
Gene Information
human ... PTGS2(5743)
Safety Information
Risk Statements
40
GHS Pictograms
Respiratory sensitization, category 1
Germ cell mutagenicity, categories 1A,1B,2
Carcinogenicity, categories 1A,1B,2
Reproductive toxicity, categories 1A,1B,2
Specific Target Organ Toxicity – Single exposure, categories 1,2
Specific Target Organ Toxicity – Repeated exposure, categories 1,2
Aspiration Hazard, category 1
GHS Signal Word
Warning
GHS Precautionary statements
P281
RTECS
TU3850000
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
German water hazard class
3
GHS Hazard statements
H351
European Hazard Symbols
Harmful (Xn)Safety Statements
22-36
Physical Property
Melting Point
262-263 °C(lit.)
Molecule Details
Biochem/physiol Actions
Triamcinolone is a synthetic glucocorticoid agonist; induces gene expression and apoptosis; inhibits prostaglandin synthesis; impairs tumor necrosis factor (TNF)-α-induced degradation of κB-α; potentiates the differentiation-inducing effects of bone morphogenetic proteins (BMP-2, -4, -6).
包装
1, 5 g in glass bottle
50, 250 mg in glass bottle
Triamcinolone is a synthetic glucocorticoid agonist; induces gene expression and apoptosis; inhibits prostaglandin synthesis; impairs tumor necrosis factor (TNF)-α-induced degradation of κB-α; potentiates the differentiation-inducing effects of bone morphogenetic proteins (BMP-2, -4, -6).
包装
1, 5 g in glass bottle
50, 250 mg in glass bottle
Molecular Spectra
No Data Available
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References
No Data Available
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