Substance

ID:183606

P1,P4-Di(guanosine-5′) tetraphosphate ammonium salt

Names and Identifiers
IUPAC name
ammonium {[5-(2-amino-6-oxo-6,9-dihydro-3H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}({[({[({[5-(2-amino-6-oxo-6,9-dihydro-3H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)(hydroxy)phosphoryl]oxy})phosphinic acid
Synonyms
Diguanosine tetraphosphateG(5′)P4(5′)GGP4GP1,P4-Di(guanosine-5′) tetraphosphate ammonium salt
IUPAC Traditional name
ammonium [5-(2-amino-6-oxo-3H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy[({[5-(2-amino-6-oxo-3H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy(hydroxy)phosphoryl}oxy(hydroxy)phosphoryl)oxy(hydroxy)phosphoryl]oxyphosphinic acid
Registration numbers
MDL Number
CAS Number
PubChem SID
Properties
Product Information
Purity
~95% (HPLC)
Safety Information
German water hazard class
3
Personal Protective Equipment
Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Storage Temperature
-20°C
Molecule Details
Application
P1,P4-Di(guanosine-5′) tetraphosphate (Diguanosine tetraphosphate) (GP4G) is a dinucleoside polyphosphate which may be used to study potential pathological effects of dinucleoside polyphosphtes in vivo. GP4G is an acceptor molecule for cytidine-3′, 5′-bisphosphate from the adenylylated donor 5′-adenylylated cytidine 5′,3′-bisphosphate in the T4 RNA ligase catalyzed reactions. GP4G is a used as an inhibitor of DNA apurinic/apyrimidinic endonuclease (APE1).
Molecular Spectra
No Data Available
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References
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