Substance
ID:183571
Names and Identifiers
IUPAC name
2,5-dioxopyrrolidin-1-yl 4-[(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)methyl]cyclohexane-1-carboxylate
Synonyms
4-(N-Maleimidomethyl)cyclohexanecarboxylic acid N-hydroxysuccinimide esterSMCCN-琥珀酰亚胺基4-(马来酰亚胺基甲基)环己烷羧酸酯4-(N-马来酰亚胺基甲基)环己烷-1-羧酸琥珀酰亚胺酯
IUPAC Traditional name
SMCC
Registration numbers
CAS Number
Beilstein Number
MDL Number
PubChem SID
Properties
Safety Information
GHS Precautionary statements
P261-P305+P351+P338
Risk Statements
36/37/38
GHS Signal Word
Warning
GHS Hazard statements
H315-H319-H335
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Storage Temperature
-20°C
German water hazard class
3
GHS Pictograms
Acute toxicity (oral, dermal, inhalation), category 4
Skin irritation, category 2
Eye irritation, category 2
Skin sensitisation, category 1
Specific Target Organ Toxicity – Single exposure, category 3
Safety Statements
26-36
European Hazard Symbols
Irritant (Xi)Product Information
Shipped in
wet ice
Purity
≥98%
Physical Property
Solubility
DMF: soluble
chloroform: soluble50 mg/mL
Melting Point
180-182 °C(lit.)
Apperance
powder
Molecule Details
Application
A heterobifunctional cross-linking reagent incorporating an extended spacer with amine and sulfhydryl reactivity. Typically coupled initially to molecules containing primary amine by amide bond buffered at pH 7.5 (6.5-8.5). The second coupling is specific for molecules containing free sulfhydryl by thioether linkage buffered at pH 6.8 (6.5-7.0). Useful for preparation of enzyme immunoconjugates and hapten carrier molecule conjugates. Contains 9 atom linker. An extended aliphatic spacer stabilizes the maleimide prior to coupling compared to aromatic spacers.
A heterobifunctional cross-linking reagent incorporating an extended spacer with amine and sulfhydryl reactivity. Typically coupled initially to molecules containing primary amine by amide bond buffered at pH 7.5 (6.5-8.5). The second coupling is specific for molecules containing free sulfhydryl by thioether linkage buffered at pH 6.8 (6.5-7.0). Useful for preparation of enzyme immunoconjugates and hapten carrier molecule conjugates. Contains 9 atom linker. An extended aliphatic spacer stabilizes the maleimide prior to coupling compared to aromatic spacers.
Molecular Spectra
No Data Available
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References
No Data Available
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