Substance
ID:183546
Names and Identifiers
IUPAC name
sodium (2S,5R,6R)-6-[(2R)-2-amino-2-phenylacetamido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate
IUPAC Traditional name
sodium ampicillin(1-)
Synonyms
Ampicillin sodium salt氨苄西林 钠盐氨苄青霉素 钠盐
Registration numbers
CAS Number
EC Number
Beilstein Number
MDL Number
PubChem SID
Properties
Physical Property
Solubility
H2O: soluble50 mg/mL (Stock solutions should be stored at -20 °C.)
Melting Point
215 °C (dec.)(lit.)
Apperance
white with slight yellow cast powder
Safety Information
GHS Hazard statements
H317-H334
RTECS
XH8400000
GHS Signal Word
Danger
German water hazard class
2
Risk Statements
42/43
Storage Temperature
2-8°C
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
GHS Pictograms
Respiratory sensitization, category 1
Germ cell mutagenicity, categories 1A,1B,2
Carcinogenicity, categories 1A,1B,2
Reproductive toxicity, categories 1A,1B,2
Specific Target Organ Toxicity – Single exposure, categories 1,2
Specific Target Organ Toxicity – Repeated exposure, categories 1,2
Aspiration Hazard, category 1
GHS Precautionary statements
P261-P280-P342+P311
Safety Statements
22-36/37-45
European Hazard Symbols
Harmful (Xn)Product Information
Suitability
suitable for cell culture
Potency
≥845 μg per mg
Molecule Details
Application
建议以 100mg/L 的抗菌用量用于细胞培养基中。 建议以 20-125μg/ml 的量用于氨苄西林抗性研究。 在 37°C 下可稳定 3 天。
Biochem/physiol Actions
β-内酰胺类抗生素，具有连接到青霉素结构上的氨基侧链。青霉素衍生物，通过灭活细菌细胞膜内表面上的转肽酶，抑制细菌细胞壁的合成（肽聚糖交联）。仅对生长的 Escherichia coli 具有杀菌作用。抗性方式：通过 β-内酰胺酶使氨苄西林的 β-内酰胺环分裂。抗菌谱：革兰氏阴性和革兰氏阳性细菌。
Protocols & Applications
Antibiotic Selector for application, solubility, solution stability, working concentration, and mode of action information
建议以 100mg/L 的抗菌用量用于细胞培养基中。 建议以 20-125μg/ml 的量用于氨苄西林抗性研究。 在 37°C 下可稳定 3 天。
Biochem/physiol Actions
β-内酰胺类抗生素，具有连接到青霉素结构上的氨基侧链。青霉素衍生物，通过灭活细菌细胞膜内表面上的转肽酶，抑制细菌细胞壁的合成（肽聚糖交联）。仅对生长的 Escherichia coli 具有杀菌作用。抗性方式：通过 β-内酰胺酶使氨苄西林的 β-内酰胺环分裂。抗菌谱：革兰氏阴性和革兰氏阳性细菌。
Protocols & Applications
Antibiotic Selector for application, solubility, solution stability, working concentration, and mode of action information
Molecular Spectra
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References
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