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Substance
ID:183533
Structure
Similarity
Functional Group
Text
ID:856
Eserine
Sigma Aldrich
ID: E8375
Names and Identifiers
IUPAC name
(3aS,8aR)-1,3a,8-trimethyl-1H,2H,3H,3aH,8H,8aH-pyrrolo[2,3-b]indol-5-yl N-methylcarbamate
IUPAC Traditional name
physostigmine
Synonyms
伊色林
毒扁豆碱
Eserine
Registration numbers
CAS Number
57-47-6
Beilstein Number
91230
EC Number
200-332-8
MDL Number
MFCD00151090
PubChem SID
24277867
Properties
Safety Information
Personal Protective Equipment
Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
RTECS
TJ2100000
GHS Pictograms
Acute toxicity (oral, dermal, inhalation), categories 1,2,3
GHS Signal Word
Danger
Packing Group
1
RID/ADR
UN 1544 6.1/PG 1
Risk Statements
26/28
UN Number
1544
European Hazard Symbols
Highly toxic (T+)
GHS Precautionary statements
P260
-
P264
-
P284
-
P310
Hazard Class
6.1
Safety Statements
25
-
45
German water hazard class
3
GHS Hazard statements
H300
-
H330
Pharmacology Properties
Gene Information
human ... ACHE(43), APP(351), BCHE(590)mouse ... Ache(11423), Bche(12038), Chrm1(12669)rat ... Ache(83817), Bche(65036), Chrm2(81645)
Product Information
Purity
≥99% (HPLC)
Physical Property
Melting Point
102-104 °C(lit.)
Molecule Details
包装
1, 5 g in glass bottle
250 mg in glass bottle
Biochem/physiol Actions
乙酰胆碱酯酶抑制剂越过血脑屏障并与乙酰胆碱酯酶形成缓慢降解的氨基甲酰酶络合物。
Molecular Spectra
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References
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Properties
Molecule Details
Molecular Spectra
References