Substance
ID:183524
Names and Identifiers
Synonyms
PhominCytochalasin B from Drechslera dematioidea细胞松弛素 B 来源于Drechslera dematioidea
IUPAC name
(5R,9R,13S,15S,15aS,16S,18aS,18bS)-16-benzyl-5,13-dihydroxy-9,15-dimethyl-14-methylidene-2H,5H,6H,7H,8H,9H,10H,13H,14H,15H,15aH,16H,17H,18H,18bH-oxacyclotetradeca[3,2-e]isoindole-2,18-dione
IUPAC Traditional name
cytochalasin B
Registration numbers
Beilstein Number
EC Number
PubChem SID
CAS Number
MDL Number
Properties
Product Information
Purity
≥98% (HPLC)
Quality Level
PREMIUM
Safety Information
GHS Pictograms
Respiratory sensitization, category 1
Germ cell mutagenicity, categories 1A,1B,2
Carcinogenicity, categories 1A,1B,2
Reproductive toxicity, categories 1A,1B,2
Specific Target Organ Toxicity – Single exposure, categories 1,2
Specific Target Organ Toxicity – Repeated exposure, categories 1,2
Aspiration Hazard, category 1
Acute toxicity (oral, dermal, inhalation), categories 1,2,3
Risk Statements
63-26/27/28
Packing Group
2
GHS Signal Word
Danger
Personal Protective Equipment
Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
RID/ADR
UN 1544 6.1/PG 2
European Hazard Symbols
Highly toxic (T+)Storage Temperature
-20°C
GHS Hazard statements
H300-H310-H330-H361
Safety Statements
28-36/37-45
UN Number
1544
German water hazard class
3
GHS Precautionary statements
P260-P264-P280-P284-P301+P310-P302+P350
RTECS
RO0205000
Hazard Class
6.1
Physical Property
Apperance
white powder
Solubility
DMSO: soluble10 mg/mL
Molecule Details
Biochem/physiol Actions
One of a group of fungal metabolites that interfere with a wide variety of cellular movements. Useful tool for characterizing some of the polymerization properties of actin,1 and in studies on cytokinesis.2 Probe for the two hexose-transport systems in rat L6 myoblasts.3
Cell permeable fungal toxin that disrupts contractile microfilaments by inhibiting actin polymerization. This, in turn, induces DNA fragmentation, inhibits cell division, and disrupts many cell processes. Inhibits glucose transport.
One of a group of fungal metabolites that interfere with a wide variety of cellular movements. Useful tool for characterizing some of the polymerization properties of actin,1 and in studies on cytokinesis.2 Probe for the two hexose-transport systems in rat L6 myoblasts.3
Cell permeable fungal toxin that disrupts contractile microfilaments by inhibiting actin polymerization. This, in turn, induces DNA fragmentation, inhibits cell division, and disrupts many cell processes. Inhibits glucose transport.
Molecular Spectra
No Data Available
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References
No Data Available
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