Substance
ID:183373
Names and Identifiers
IUPAC name
(2S,5R,6R)-6-[(2R)-2-amino-2-phenylacetamido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid trihydrate
IUPAC Traditional name
ampicillin trihydrate
Synonyms
氨苄青霉素Ampicillin trihydrate氨苄西林 三水合物
Registration numbers
MDL Number
Beilstein Number
EC Number
CAS Number
PubChem SID
Properties
Safety Information
RTECS
XH8425000
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
GHS Signal Word
Danger
German water hazard class
2
Storage Temperature
2-8°C
GHS Pictograms
Respiratory sensitization, category 1
Germ cell mutagenicity, categories 1A,1B,2
Carcinogenicity, categories 1A,1B,2
Reproductive toxicity, categories 1A,1B,2
Specific Target Organ Toxicity – Single exposure, categories 1,2
Specific Target Organ Toxicity – Repeated exposure, categories 1,2
Aspiration Hazard, category 1
Acute toxicity (oral, dermal, inhalation), category 4
Skin irritation, category 2
Eye irritation, category 2
Skin sensitisation, category 1
Specific Target Organ Toxicity – Single exposure, category 3
GHS Precautionary statements
P261-P280-P305+P351+P338-P342+P311
GHS Hazard statements
H315-H317-H319-H334-H335
Risk Statements
36/37/38-42/43
European Hazard Symbols
Harmful (Xn)Safety Statements
22-26-36/37
Physical Property
Melting Point
198-200 °C (dec.)(lit.)
Product Information
Purity
96.0-100.5% anhydrous basis (HPLC)
Molecule Details
Biochem/physiol Actions
A β-lactam antibiotic with an amino group side chain attached to the penicillin structure. Penicillin derivative that inhibits bacterial cell-wall synthesis (peptidoglycan cross-linking) by inactivating transpeptidases on the inner surface of the bacterial cell membrane. Bactericidal only to growing Escherichia coli . Mode of resistance: Cleavage of β-lactam ring of ampicillin by β-lactamase. Antimicrobial spectrum: Gram-negative and Gram-positive bacteria.
Application
Ampicillin Trihydrate is commonly used to select for ampicillin resistance in mutated and transformed cells.
A β-lactam antibiotic with an amino group side chain attached to the penicillin structure. Penicillin derivative that inhibits bacterial cell-wall synthesis (peptidoglycan cross-linking) by inactivating transpeptidases on the inner surface of the bacterial cell membrane. Bactericidal only to growing Escherichia coli . Mode of resistance: Cleavage of β-lactam ring of ampicillin by β-lactamase. Antimicrobial spectrum: Gram-negative and Gram-positive bacteria.
Application
Ampicillin Trihydrate is commonly used to select for ampicillin resistance in mutated and transformed cells.
Molecular Spectra
No Data Available
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References
No Data Available
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