Substance

ID:183231

Names and Identifiers
IUPAC name
(4R,10S,13S,16S,19S,22S,25S,28S,31S,34S,37R)-19,34-bis(4-aminobutyl)-37-{2-[(2S)-2-aminopropanamido]acetamido}-13,25,28-tribenzyl-31-(carbamoylmethyl)-10,16-bis[(1R)-1-hydroxyethyl]-7-(hydroxymethyl)-22-(1H-indol-3-ylmethyl)-6,9,12,15,18,21,24,27,30,33,36-undecaoxo-1,2-dithia-5,8,11,14,17,20,23,26,29,32,35-undecaazacyclooctatriacontane-4-carboxylic acid
Synonyms
Somatostatin生长激素释放抑制因子SRIF促生长素释放抑制因子生长抑素-14生长抑素
IUPAC Traditional name
(4R,10S,13S,16S,19S,22S,25S,28S,31S,34S,37R)-19,34-bis(4-aminobutyl)-37-{2-[(2S)-2-aminopropanamido]acetamido}-13,25,28-tribenzyl-31-(carbamoylmethyl)-10,16-bis[(1R)-1-hydroxyethyl]-7-(hydroxymethyl)-22-(1H-indol-3-ylmethyl)-6,9,12,15,18,21,24,27,30,33,36-undecaoxo-1,2-dithia-5,8,11,14,17,20,23,26,29,32,35-undecaazacyclooctatriacontane-4-carboxylic acid
Registration numbers
EC Number
Beilstein Number
CAS Number
MDL Number
PubChem SID
Properties
Safety Information
Personal Protective Equipment
Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Storage Temperature
-20°C
RTECS
WF8751700
German water hazard class
3
Pharmacology Properties
Gene Information
human ... SSTR1(6751), SSTR2(6752), SSTR3(6753), SSTR4(6754), SSTR5(6755)
Product Information
Potency
0.3-50 ng/mL
Suitability
suitable for cell culture
Sterility
γ-irradiated
Physical Property
Apperance
powder
Solubility
cell culture medium: soluble10 mL/vial
Molecule Details
Amino Acid Sequence
Ala-Gly-Cys-Lys-Asn-Phe-Phe-Trp-Lys-Thr-Phe-Thr-Ser-Cys
Biochem/physiol Actions
Somatostatin regulates endocrine function and cell proliferation via interaction with G-protein-coupled somatostatin receptors. It exists in two active forms produced by alternative cleavage of a single preproprotein (14 aa and 28 aa forms). Somatosatin inhibits the release of growth hormone; thyroid-stimulating hormone and a range of gastrointestinal hormones: Cholecystokinin (CCK); Enteroglucagon; Gastrin; Gastric inhibitory polypeptide (GIP); Motilin; Secretin; Vasoactive intestinal peptide (VIP).
Reconstitution
加入 10mL 无菌培养基可制成 2μg/mL 的储存液。
Physical form
0°C 下为粉末状;分成小份冻存,以避免使用时重复冰冻/解冻
Molecular Spectra
No Data Available
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References
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