Substance
ID:183171
Names and Identifiers
IUPAC Traditional name
5a-pregnane-3,20-dione
IUPAC name
(1S,2S,7S,10R,11S,14S,15S)-14-acetyl-2,15-dimethyltetracyclo[8.7.0.02,7.011,15]heptadecan-5-one
Synonyms
5α-Pregnane-3,20-dione (allo)5α-DihydroprogesteroneAllopregnane-3,20-dione
Properties
Safety Information
German water hazard class
3
Personal Protective Equipment
Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
RTECS
TU4157150
Molecule Details
Biochem/physiol Actions
A high-level metabolite of progesterone in breast cancer tissue (but not normal breast tissue); promotes cell proliferation and detachment. Receptors appear only on the cell surface of MCF-7 breast cancer cells, not on nuclei where most other steroid receptors are located.1
A high-level metabolite of progesterone in breast cancer tissue (but not normal breast tissue); promotes cell proliferation and detachment. Receptors appear only on the cell surface of MCF-7 breast cancer cells, not on nuclei where most other steroid receptors are located.1
Molecular Spectra
No Data Available
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References
No Data Available
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