Substance
ID:183150
Names and Identifiers
Synonyms
Misoprostol(±)-15-Deoxy-(16RS)-16-hydroxy-16-methylprostaglandin E1 methyl ester
IUPAC Traditional name
misoprostol
IUPAC name
methyl 7-[(1R,2R,3R)-3-hydroxy-2-[(1E)-4-hydroxy-4-methyloct-1-en-1-yl]-5-oxocyclopentyl]heptanoate
Properties
Safety Information
GHS Precautionary statements
P201-P301+P310-P308+P313
RID/ADR
UN 2810 6.1/PG 3
Storage Temperature
-20°C
UN Number
2810
GHS Pictograms
Acute toxicity (oral, dermal, inhalation), categories 1,2,3
Respiratory sensitization, category 1
Germ cell mutagenicity, categories 1A,1B,2
Carcinogenicity, categories 1A,1B,2
Reproductive toxicity, categories 1A,1B,2
Specific Target Organ Toxicity – Single exposure, categories 1,2
Specific Target Organ Toxicity – Repeated exposure, categories 1,2
Aspiration Hazard, category 1
GHS Hazard statements
H301-H360
European Hazard Symbols
Toxic (T)Safety Statements
53-45
Risk Statements
60-61-25
Hazard Class
6.1
GHS Signal Word
Danger
Packing Group
3
German water hazard class
3
Pharmacology Properties
Gene Information
human ... PTGIR(5739)
Product Information
Purity
≥99% (TLC)
Molecule Details
Biochem/physiol Actions
Cytoprotective PGE1 analog that prevents NSAID-induced gastric ulceration.
PGE1 analog prodrug which is rapidly de-esterified to active "misoprostolic acid". Cited for extremely wide-ranging therapeutic effects, including prevention of NSAID-induced gastric ulceration, regulation of immunologic cascades, inhibition of platelet-activating factor (PAF), treatment of ethanol- and acetaminophen-induced hepatotoxicity and hepatitis, and stimulation of cartilage repair after injury.1
Cytoprotective PGE1 analog that prevents NSAID-induced gastric ulceration.
PGE1 analog prodrug which is rapidly de-esterified to active "misoprostolic acid". Cited for extremely wide-ranging therapeutic effects, including prevention of NSAID-induced gastric ulceration, regulation of immunologic cascades, inhibition of platelet-activating factor (PAF), treatment of ethanol- and acetaminophen-induced hepatotoxicity and hepatitis, and stimulation of cartilage repair after injury.1
Molecular Spectra
No Data Available
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References
No Data Available
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