Substance
ID:183030
Names and Identifiers
IUPAC Traditional name
1-[2-(trifluoromethyl)phenyl]imidazole
IUPAC name
1-[2-(trifluoromethyl)phenyl]-1H-imidazole
Synonyms
TRIM1-[2-(Trifluoromethyl)phenyl]imidazole
Properties
Safety Information
European Hazard Symbols
Irritant (Xi)Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
GHS Pictograms
Acute toxicity (oral, dermal, inhalation), category 4
Skin irritation, category 2
Eye irritation, category 2
Skin sensitisation, category 1
Specific Target Organ Toxicity – Single exposure, category 3
GHS Hazard statements
H315-H319-H335
German water hazard class
3
Risk Statements
36/37/38
Safety Statements
26-36
Storage Temperature
2-8°C
GHS Precautionary statements
P261-P305+P351+P338
GHS Signal Word
Warning
Pharmacology Properties
Gene Information
human ... NOS1(4842), NOS2(4843), NOS2B(201288), NOS2C(645740), NOS3(4846)
Molecule Details
Biochem/physiol Actions
Potent nitric oxide synthase inhibitor. Because of the putative involvement of nitric oxide in depression and stress syndromes, TRIM was studied for its antidepressant effects, and found to reduce manifestations of stress in an animal model as well as fluoxetine.1
Potent nitric oxide synthase inhibitor. Because of the putative involvement of nitric oxide in depression and stress syndromes, TRIM was studied for its antidepressant effects, and found to reduce manifestations of stress in an animal model as well as fluoxetine.1
Molecular Spectra
No Data Available
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References
No Data Available
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