Substance

ID:182916

Fumonisin B2 from Fusarium moniliforme

Names and Identifiers
IUPAC name
2-[2-({19-amino-6-[(3,4-dicarboxybutanoyl)oxy]-16,18-dihydroxy-5,9-dimethylicosan-7-yl}oxy)-2-oxoethyl]butanedioic acid
Synonyms
Fumonisin B2 from Fusarium moniliforme
IUPAC Traditional name
fumonisin B2
Registration numbers
CAS Number
PubChem SID
MDL Number
Properties
Safety Information
GHS Pictograms
GHS06
Acute toxicity (oral, dermal, inhalation), categories 1,2,3
GHS08
Respiratory sensitization, category 1
Germ cell mutagenicity, categories 1A,1B,2
Carcinogenicity, categories 1A,1B,2
Reproductive toxicity, categories 1A,1B,2
Specific Target Organ Toxicity – Single exposure, categories 1,2
Specific Target Organ Toxicity – Repeated exposure, categories 1,2
Aspiration Hazard, category 1
GHS Signal Word
Danger
Packing Group
1
UN Number
2811
RTECS
TZ8335000
Storage Temperature
-20°C
GHS Hazard statements
H300-H310-H315-H319-H330-H335-H351
European Hazard Symbols
Highly toxic Highly toxic (T+)
German water hazard class
3
GHS Precautionary statements
P260-P264-P280-P284-P302+P350-P305+P351+P338
Risk Statements
26/27/28-36/37/38-40
RID/ADR
UN 2811 6.1/PG 1
Hazard Class
6.1
Safety Statements
22-36/37/39-45
Personal Protective Equipment
Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
Molecule Details
Biochem/physiol Actions
Inhibitor of sphingosine N-acyltransferase. Blocks the formation of ceramide from sphingosine.
General description
Mycotoxin originally isolated from Fusarium sp, which grows on corn. Produces neural tube defects and craniofacial abnormalities in fetuses.1 Many strains of Aspergillus niger growing naturally on grapes are capable of producing fumonisin B2,2 so it is now a concern for human consumption of grapes, raisins, and wine.
Molecular Spectra
No Data Available
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References
No Data Available
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