Substance

ID:1828872

Names and Identifiers
IUPAC name
2-[(5Z)-5-[(2E)-2-methyl-3-phenylprop-2-en-1-ylidene]-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]acetic acid
IUPAC Traditional name
kinedak
Synonyms
epalrestat5-((1Z,2E)-2-methyl-3-phenylpropenylidene)-4-oxo-2-thioxo-3-thiazolidineacetic acid5-((Z,E)-beta-methylcinnamylidene)-4-oxo-2-thioxo-3-thiazolidineacetic acidONO 2ONO-2ONO-2235Ono 2235
International Nonproprietary Name (INN)
epalrestatepalrestatum
Brand Name
Kinedak
Registration numbers
CAS Number
PubChem CID
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SABIO-RK Database
SureChEMBL Database
UniProt Database
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CHEBI ID
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Properties
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Molecule Details
A monocarboxylic acid that is 1,3-thiazolidine which is substituted on the nitrogen by a carboxymethyl group, at positions 2 and 4 by thioxo and oxo groups, respectively, and at position 5 by a 2-methyl-3-phenylprop-2-en-1-ylidene group. It is an inhibitor of aldose reductase (which catalyses the conversion of glucose to sorbitol) and is used for the treatment of some diabetic complications, including neuropathy.
Molecular Spectra
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References
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