Substance

ID:1828786

Names and Identifiers
IUPAC name
2-amino-3-hydroxy-N'-[(2,3,4-trihydroxyphenyl)methyl]propanehydrazide hydrochloride
IUPAC Traditional name
benserazide hydrochloride
Synonyms
benserazide hydrochloride2'-(2,3,4-trihydroxybenzyl)-DL-serinohydrazide monohydrochloride3-hydroxy-1-oxo-1-[2-(2,3,4-trihydroxybenzyl)hydrazinyl]propan-2-aminium chlorideDL-serine 2-(2,3,4-trihydroxybenzyl)hydrazine hydrochlorideRo 4-4602/001benserazide HCl
Registration numbers
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PubChem CID
Reaxys Registry
ACToR Database
CompTox Database
SureChEMBL Database
KEGG DRUG Database
CHEBI ID
PubChem SID
Properties
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Molecule Details
A hydrochloride that is the monohydrochloride salt of benserazide. An aromatic-L-amino-acid decarboxylase inhibitor (DOPA decarboxylase inhibitor) that does not enter the central nervous system, it is used as an adjunct to levodopa in the treatment of parkinsonism. By preventing the conversion of levodopa to dopamine in the periphery, it causes an increase in the amount of levodopa reaching the central nervous system and so reduces the required dose. Benserazide hydrochloride has no antiparkinson actions when given alone.
Molecular Spectra
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References
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