Substance
ID:182858
Names and Identifiers
IUPAC Traditional name
sodium piperacillin(1-)
Synonyms
Piperacillin sodium salt
IUPAC name
sodium (2S,5R,6R)-6-[(2R)-2-[(4-ethyl-2,3-dioxopiperazine-1-carbonyl)amino]-2-phenylacetamido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate
Registration numbers
CAS Number
Beilstein Number
EC Number
MDL Number
Properties
Safety Information
German water hazard class
2
RTECS
XI0180000
Storage Temperature
2-8°C
Personal Protective Equipment
Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Molecule Details
Application
Piperacillin is a semisynthetic, broad-spectrum ureidopenicillin antibiotic. It is derived from ampicillin. It has been used in pharmacokinetic studies in order to optimize antimicrobial therapy in patients with sepsis1. It is used to study piperacillin hypersensitivity reactions2 and to study multidrug-resistant organisms3.
Biochem/physiol Actions
Piperacillin inhibits the final stage of bacterial cell wall biosynthesis at the level of PBP binding.
Piperacillin inhibits the last stage of bacterial cell wall synthesis by binding to certain penicillin-binding proteins (PBPs), which results in cell lysis. Cell lysis is mediated by bacterial cell wall autolytic enzymes. Piperacillin may interfere with autolysin inhibitors.
Piperacillin is a semisynthetic, broad-spectrum ureidopenicillin antibiotic. It is derived from ampicillin. It has been used in pharmacokinetic studies in order to optimize antimicrobial therapy in patients with sepsis1. It is used to study piperacillin hypersensitivity reactions2 and to study multidrug-resistant organisms3.
Biochem/physiol Actions
Piperacillin inhibits the final stage of bacterial cell wall biosynthesis at the level of PBP binding.
Piperacillin inhibits the last stage of bacterial cell wall synthesis by binding to certain penicillin-binding proteins (PBPs), which results in cell lysis. Cell lysis is mediated by bacterial cell wall autolytic enzymes. Piperacillin may interfere with autolysin inhibitors.
Molecular Spectra
No Data Available
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References
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