Substance
ID:182794
Names and Identifiers
IUPAC name
{[(2R,3R,5R,7S,8S,9R)-2-[(1S,3S,4S,5R,6R,7E,9E,11E,13Z)-14-cyano-3,5-dihydroxy-1-methoxy-4,6,8,9,13-pentamethyltetradeca-7,9,11,13-tetraen-1-yl]-7-[(2E)-3-{2-[(2S)-4-[(2S,3S,4S)-4-(dimethylamino)-2,3-dihydroxy-5-methoxypentanamido]butan-2-yl]-1,3-oxazol-4-yl}prop-2-en-1-yl]-9-hydroxy-4,4,8-trimethyl-1,6-dioxaspiro[4.5]decan-3-yl]oxy}phosphonic acid
IUPAC Traditional name
[(2R,3R,5R,7S,8S,9R)-2-[(1S,3S,4S,5R,6R,7E,9E,11E,13Z)-14-cyano-3,5-dihydroxy-1-methoxy-4,6,8,9,13-pentamethyltetradeca-7,9,11,13-tetraen-1-yl]-7-[(2E)-3-{2-[(2S)-4-[(2S,3S,4S)-4-(dimethylamino)-2,3-dihydroxy-5-methoxypentanamido]butan-2-yl]-1,3-oxazol-4-yl}prop-2-en-1-yl]-9-hydroxy-4,4,8-trimethyl-1,6-dioxaspiro[4.5]decan-3-yl]oxyphosphonic acid
Synonyms
Calyculin A from Discodermia calyx
Registration numbers
CAS Number
Beilstein Number
PubChem SID
MDL Number
Properties
Product Information
Purity
≥90% (HPLC)
Safety Information
GHS Pictograms
Acute toxicity (oral, dermal, inhalation), categories 1,2,3
Hazard Class
6.1
German water hazard class
3
RID/ADR
UN 3462 6.1/PG 3
GHS Signal Word
Danger
GHS Precautionary statements
P261-P280-P301+P310-P311
Risk Statements
23/24/25-38
Storage Temperature
-20°C
Packing Group
3
Safety Statements
36/37/39-45
Personal Protective Equipment
Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
GHS Hazard statements
H301-H311-H315-H331
European Hazard Symbols
Toxic (T)UN Number
3462
Physical Property
Apperance
white solid
Solubility
ethanol: soluble
DMSO: soluble
Molecule Details
Biochem/physiol Actions
Inhibitor of protein phosphatases types 1 and 2A; marine toxin, potent tumor promotor.
Inhibitor of protein phosphatases types 1 and 2A; marine toxin, potent tumor promotor.
Molecular Spectra
No Data Available
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References
No Data Available
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