Substance
ID:182762
Names and Identifiers
IUPAC Traditional name
tetralithium(1+) ion [(2R,3S,4R,5R)-5-(2-amino-6-oxo-1H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl [dioxido(sulfanylidene)-λ5-phosphanyl phosphonato]oxyphosphonate
Synonyms
Guanosine 5′-[γ-thio]triphosphate tetralithium saltGuanosine 5′-O-(3-thiotriphosphate) tetralithium saltGTPγS tetralithium saltGTP-γ-S-Li4
IUPAC name
tetralithium(1+) ion [(2R,3S,4R,5R)-5-(2-amino-6-oxo-6,9-dihydro-1H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl {[dioxido(sulfanylidene)-λ5-phosphanyl phosphonato]oxy}phosphonate
Registration numbers
CAS Number
MDL Number
Beilstein Number
EC Number
PubChem SID
Properties
Safety Information
GHS Signal Word
Warning
GHS Hazard statements
H315-H319-H335
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Safety Statements
26-36
Risk Statements
36/37/38
European Hazard Symbols
Irritant (Xi)German water hazard class
3
GHS Precautionary statements
P261-P305+P351+P338
Storage Temperature
-20°C
GHS Pictograms
Acute toxicity (oral, dermal, inhalation), category 4
Skin irritation, category 2
Eye irritation, category 2
Skin sensitisation, category 1
Specific Target Organ Toxicity – Single exposure, category 3
Product Information
Purity
≥75% (HPLC)
Shipped in
dry ice
Physical Property
Apperance
off-white powder
Solubility
H2O: ≥75 mg/mL (Solutions are very unstable; prepare immediately prior to use.)
Molecule Details
Biochem/physiol Actions
GTP-γ-S is a non-hydrolyzable GTP analog, known for its role as a G-protein activator. It has recently been shown to protect proteins from proteolytic degradation, stimulate GLUT4 translocation in a tyrosine kinase-dependent manner, stimulate phospholipases and induce actin polymerization in vitro.
GTP-γ-S is a non-hydrolyzable GTP analog, known for its role as a G-protein activator. It has recently been shown to protect proteins from proteolytic degradation, stimulate GLUT4 translocation in a tyrosine kinase-dependent manner, stimulate phospholipases and induce actin polymerization in vitro.
Molecular Spectra
No Data Available
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References
No Data Available
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