Substance
ID:1826053
Names and Identifiers
IUPAC name
(2S)-1-[(2S)-5-carbamimidamido-2-[(2S)-2-[(2R)-2-[(2S)-2-[(2S)-3-hydroxy-2-[(2S)-2-[(2S)-3-(1H-imidazol-4-yl)-2-{[(2S)-5-oxopyrrolidin-2-yl]formamido}propanamido]-3-(1H-indol-3-yl)propanamido]propanamido]-3-(4-hydroxyphenyl)propanamido]-4-methylpentanamido]-4-methylpentanamido]pentanoyl]-N-ethylpyrrolidine-2-carboxamide
IUPAC Traditional name
leuprorelin
Synonyms
leuprolide(D-Leu(6),des-Gly-NH2(10),Pro-ethylamide(9))-gonadotropin-releasing hormoneL-pyroglutamyl-L-histidyl-L-tryptophyl-L-seryl-L-tyrosyl-D-leucyl-L-leucyl-L-arginyl-L-proline ethylamideLeuprorelinpGlu-His-Trp-Ser-Tyr-D-Leu-Leu-Arg-Pro-NHC2H5pGlu-His-Trp-Ser-Tyr-D-Leu-Leu-Arg-Pro-NHEt
International Nonproprietary Name (INN)
leuprorelinaleuprorelineleuprorelinum
Registration numbers
PubChem CID
CAS Number
KEGG ID
Reaxys Registry
CHEMBL
CompTox Database
MetaboLights Database
SureChEMBL Database
DrugBank ID
Drug Central Database
KEGG DRUG Database
CHEBI ID
PubChem SID
Properties
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Molecule Details
An oligopeptide comprising pyroglutamyl, histidyl, tryptophyl, seryl, tyrosyl, D-leucyl, leucyl, arginyl, and N-ethylprolinamide residues joined in sequence. It is a synthetic nonapeptide analogue of gonadotropin-releasing hormone, and is used as a subcutaneous hydrogel implant (particularly as the acetate salt) for the treatment of prostate cancer and for the suppression of gonadal sex hormone production in children with central precocious puberty.
Molecular Spectra
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References
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