Substance

ID:182602

MolImageID:134

5-Iodo-2′-deoxyuridine

Sigma Aldrich
Names and Identifiers
Synonyms
1-(2-Deoxy-β-D-ribofuranosyl)-5-iodouracil5-IUdR5-Iodo-2′-deoxyuridine2′-Deoxy-5-iodouridineIDUIdUrdIdoxuridine
IUPAC Traditional name
idoxuridine
IUPAC name
1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-iodo-1,2,3,4-tetrahydropyrimidine-2,4-dione
Registration numbers
MDL Number
MFCD00134656
Beilstein Number
30397
EC Number
200-207-8
CAS Number
54-42-2
PubChem SID
24896108
Properties
Safety Information
GHS Hazard statements
H315-H319-H335-H341-H361
European Hazard Symbols
Harmful Harmful (Xn)
Storage Temperature
2-8°C
German water hazard class
3
GHS Pictograms
GHS07
Acute toxicity (oral, dermal, inhalation), category 4
Skin irritation, category 2
Eye irritation, category 2
Skin sensitisation, category 1
Specific Target Organ Toxicity – Single exposure, category 3
GHS08
Respiratory sensitization, category 1
Germ cell mutagenicity, categories 1A,1B,2
Carcinogenicity, categories 1A,1B,2
Reproductive toxicity, categories 1A,1B,2
Specific Target Organ Toxicity – Single exposure, categories 1,2
Specific Target Organ Toxicity – Repeated exposure, categories 1,2
Aspiration Hazard, category 1
Personal Protective Equipment
Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
GHS Precautionary statements
P261-P281-P305+P351+P338
RTECS
YU7700000
GHS Signal Word
Warning
Risk Statements
63-36/37/38-62-68
Safety Statements
26-36/37
Product Information
Purity
≥99% (HPLC)
Physical Property
Melting Point
194 °C(lit.)
Molecule Details
包装
5, 25 g in glass bottle
Application
5-Iodo-2′-deoxyuridine (5-IUdR; IdUrd) is a pyrimidine analog (halogenated thymidine) that has antiviral activity agains vaccinia virus (orthopoxviruses). IdUrd is used as a radiosensitizer in human cancer studies.
Molecular Spectra
No Data Available
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References
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