Substance
ID:1825669
Names and Identifiers
IUPAC name
N-(5-aminopentyl)-N-hydroxy-N'-[5-(N-hydroxy-3-{[5-(N-hydroxyacetamido)pentyl]carbamoyl}propanamido)pentyl]butanediamide
IUPAC Traditional name
deferoxamine
Synonyms
desferrioxamine BDFODFOBDeferoxaminDeferrioxamineDesferrioxamineN(4)-{5-[acetyl(hydroxy)amino]pentyl}-N(1)-(5-{4-[(5-aminopentyl)(hydroxy)amino]-4-oxobutanamido}pentyl)-N(1)-hydroxybutanediamidedeferrioxamine Bdesferrioxamine-B
International Nonproprietary Name (INN)
deferoxaminadeferoxaminedeferoxaminum
Registration numbers
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Patent number
US2001023240US2007184114EP0993831US2001003001US2002028250US2002052422US2002107266US2002155993US2003012817US2003235612US2004023847US2004068013US2004110839US2005042274US2005101671US2005119502US2005142156US2005272638US2005272815US2006210533US2006264356US2007269500US2008044827US2008167217US2008279913GB2240630US2007191368
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Properties
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Molecule Details
An acyclic desferrioxamine that is butanedioic acid in which one of the carboxy groups undergoes formal condensation with the primary amino group of N-(5-aminopentyl)-N-hydroxyacetamide and the second carboxy group undergoes formal condensation with the hydroxyamino group of N(1)-(5-aminopentyl)-N(1)-hydroxy-N(4)-[5-(hydroxyamino)pentyl]butanediamide. It is a siderophore native to Streptomyces pilosus biosynthesised by the DesABCD enzyme cluster as a high affinity Fe(III) chelator.
Molecular Spectra
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References
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