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Substance
ID:182566
Structure
Similarity
Functional Group
Text
ID:102121
Adenosine 3′,5′-cyclic monophosphate
Sigma Aldrich
ID: A9501
Names and Identifiers
Synonyms
cAMP
环化腺苷酸
腺苷环磷酸酯
Adenosine 3′,5′-cyclic monophosphate
腺苷-3′,5′-环单磷酸
IUPAC name
(4aR,6R,7R,7aS)-6-(6-amino-9H-purin-9-yl)-2,7-dihydroxy-hexahydro-1,3,5,2λ
5
-furo[3,2-d][1,3,2λ
5
]dioxaphosphinin-2-one
IUPAC Traditional name
cyclic adenosine monophosphate
Registration numbers
CAS Number
60-92-4
EC Number
200-492-9
Beilstein Number
52645
MDL Number
MFCD00005845
PubChem SID
24278245
Properties
Safety Information
Personal Protective Equipment
Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Storage Temperature
-20°C
RTECS
AU7357600
German water hazard class
3
Product Information
Purity
≥98.5% (HPLC)
Pharmacology Properties
Gene Information
human ... OPRK1(4986)
Physical Property
Solubility
H2O: soluble10 mg/mL, clear, colorless (pH of aqueous solution is approx. 3.0. The sodium salt (A6885) is about 20× more soluble.)
Apperance
white powder
Melting Point
260 °C (dec.)(lit.)
Molecule Details
包装
1, 5, 25 g in poly bottle
Biochem/physiol Actions
环化腺苷酸依赖性蛋白激酶 (PKA) 的自然活化剂。cAMP 是一种重要的第二信使,并且在很多系统中与神经递质或激素诱导的受体激活相关。已有显示,cAMP/PKA 信号通路可抑制细胞增殖,诱导分化并导致细胞凋亡。
Molecular Spectra
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