Substance
ID:182516
Names and Identifiers
IUPAC Traditional name
spermine
IUPAC name
(3-aminopropyl)({4-[(3-aminopropyl)amino]butyl})amine
Synonyms
精素肌胺肝胺精胺N,N′-双(3-氨基丙基)-1,4-丁二胺Spermine
Registration numbers
CAS Number
EC Number
Beilstein Number
PubChem SID
MDL Number
Properties
Safety Information
Personal Protective Equipment
Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
Safety Statements
26-36/37/39-45
Risk Statements
34
GHS Pictograms
Corrosive to metals, category 1
Skin corrosion, categories 1A,1B,1C
Serious eye damage, category 1
RID/ADR
UN 3259 8/PG 2
European Hazard Symbols
Corrosive (C)Packing Group
2
German water hazard class
3
GHS Signal Word
Danger
GHS Hazard statements
H314
GHS Precautionary statements
P280-P305+P351+P338-P310
UN Number
3259
Storage Temperature
2-8°C
Hazard Class
8
RTECS
EJ7175000
Product Information
Purity
≥97%
Physical Property
Melting Point
28-30(lit.)
Boiling Point
150 °C/5 mmHg(lit.)
Flash Point
110 °C
230 °F
Pharmacology Properties
Gene Information
human ... GRIN2B(2904)rat ... Grin2a(24409)
Molecule Details
包装
1, 5, 25 g in glass bottle
Biochem/physiol Actions
多胺位点混合型 NMDA 谷氨酸受体激动剂/拮抗剂。在高浓度 (1mM) 下观察到神经保护作用，而在低浓度下则观察到神经毒性。它在番木鳖碱-不敏感性甘氨酸位点能够增强激动剂效应。在细胞增殖和分化中发挥作用；抑制神经元一氧化氮合成酶 (nNOS)。
1, 5, 25 g in glass bottle
Biochem/physiol Actions
多胺位点混合型 NMDA 谷氨酸受体激动剂/拮抗剂。在高浓度 (1mM) 下观察到神经保护作用，而在低浓度下则观察到神经毒性。它在番木鳖碱-不敏感性甘氨酸位点能够增强激动剂效应。在细胞增殖和分化中发挥作用；抑制神经元一氧化氮合成酶 (nNOS)。
Molecular Spectra
No Data Available
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References
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