Substance
ID:182483
Names and Identifiers
IUPAC Traditional name
6-(phenylamino)quinoline-5,8-dione
IUPAC name
6-(phenylamino)-5,8-dihydroquinoline-5,8-dione
Synonyms
6-(Phenylamino)-5,8-quinolinedioneLY83583LY-83,5836-Anilinoquinoline-5,8-quinone
Properties
Physical Property
Solubility
methanol: soluble11 mg/mL
ethanol: soluble8 mg/mL
0.1 M HCl: soluble1 mg/mL
Apperance
violet solid
Safety Information
GHS Pictograms
Acute toxicity (oral, dermal, inhalation), category 4
Skin irritation, category 2
Eye irritation, category 2
Skin sensitisation, category 1
Specific Target Organ Toxicity – Single exposure, category 3
GHS Signal Word
Warning
Storage Temperature
2-8°C
European Hazard Symbols
Irritant (Xi)GHS Precautionary statements
P261-P305+P351+P338
GHS Hazard statements
H315-H319-H335
Risk Statements
36/37/38
Safety Statements
26-36
German water hazard class
3
Product Information
Purity
≥95% (TLC)
Molecule Details
Biochem/physiol Actions
Blocks cGMP production; inhibits intracellular Ca2+ release; blocks the effects of nitric oxide. Inhibits antigen-induced leukotriene release.
Application
6-Anilinoquinoline-5,8-quinone inhibits soluble guanylate cyclase and cGMP production. 6-Anilinoquinoline-5,8-quinone also blocks the release of intracellular Ca2+ and antigen-induced leukotrienes.
Blocks cGMP production; inhibits intracellular Ca2+ release; blocks the effects of nitric oxide. Inhibits antigen-induced leukotriene release.
Application
6-Anilinoquinoline-5,8-quinone inhibits soluble guanylate cyclase and cGMP production. 6-Anilinoquinoline-5,8-quinone also blocks the release of intracellular Ca2+ and antigen-induced leukotrienes.
Molecular Spectra
No Data Available
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References
No Data Available
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