Substance

ID:1824817

Names and Identifiers
IUPAC name
(4E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydro-2-benzofuran-5-yl)-4-methylhex-4-enoic acid
IUPAC Traditional name
mycophenolic acid
Synonyms
mycophenolic acid(E)-6-(4-Hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-4-hexenoic acidMicofenolico acidoMycophenolateMycophenolsaeure
International Nonproprietary Name (INN)
acide mycophenoliqueacido micofenolicoacidum mycophenolicummycophenolic acid
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ACToR Database
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CHEMBL
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PubChem SID
Properties
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Molecule Details
A member of the class of 2-benzofurans that is 2-benzofuran-1(3H)-one which is substituted at positions 4, 5, 6, and 7 by methyl, methoxy, (2E)-5-carboxy-3-methylpent-2-en-1-yl, and hydroxy groups, respectively. It is an antibiotic produced by Penicillium brevi-compactum, P. stoloniferum, P. echinulatum and related species. An immunosuppressant, it is widely used (partiularly as its sodium salt and as the 2-(morpholin-4-yl)ethyl ester prodrug, mycophenolate mofetil) to prevent tissue rejection following organ transplants and for the treatment of certain autoimmune diseases.
Molecular Spectra
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References
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