Substance
ID:182400
Names and Identifiers
IUPAC Traditional name
furosemide
IUPAC name
4-chloro-2-[(furan-2-ylmethyl)amino]-5-sulfamoylbenzoic acid
Synonyms
4-氯-N-呋喃基-5-氨磺酰邻氨基苯甲酸5-(氨基磺酰基)-4-氯-2-([2-呋喃甲基]氨基)苯甲酸Furosemide呋塞米
Properties
Physical Property
Melting Point
220 °C (dec.)(lit.)
Safety Information
Personal Protective Equipment
Eyeshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
European Hazard Symbols
Toxic (T)GHS Pictograms
Respiratory sensitization, category 1
Germ cell mutagenicity, categories 1A,1B,2
Carcinogenicity, categories 1A,1B,2
Reproductive toxicity, categories 1A,1B,2
Specific Target Organ Toxicity – Single exposure, categories 1,2
Specific Target Organ Toxicity – Repeated exposure, categories 1,2
Aspiration Hazard, category 1
GHS Signal Word
Danger
GHS Precautionary statements
P201-P308+P313
RTECS
CB2625000
Risk Statements
61
GHS Hazard statements
H360
German water hazard class
3
Safety Statements
53-22-36/37/39-45
Pharmacology Properties
Gene Information
human ... ALB(213), CYP1A2(1544), SLC12A1(6557)
Molecule Details
Biochem/physiol Actions
抑制肾脏中离子的协同运输。
"High ceiling" diuretic that strongly affects renal tubular action by increasing renal blood flow; antihypertensive.
抑制肾脏中离子的协同运输。
"High ceiling" diuretic that strongly affects renal tubular action by increasing renal blood flow; antihypertensive.
Molecular Spectra
No Data Available
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References
No Data Available
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