Substance

ID:1823340

Names and Identifiers
IUPAC name
4-phenylbutanoic acid
IUPAC Traditional name
4-phenylbutyric acid
Synonyms
4-phenylbutyric acid4-PHENYL-BUTANOIC ACID4-Phenyl-n-butyric acidBenzenebutyric acidPBAgamma-Phenyl-n-butyric acidgamma-phenylbutyric acidomega-Phenylbutanoic acidomega-phenylbutyric acid
Registration numbers
CAS Number
PubChem CID
LINCS Database
MetaCyc Database
Reaxys Registry
ACToR Database
CompTox Database
SureChEMBL Database
HMDB Database
PDBeChem Database
NMRShiftDB Database
Drug Central Database
BindingDB Database
PubChem SID
Properties
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Molecule Details
A monocarboxylic acid the structure of which is that of butyric acid substituted with a phenyl group at C-4. It is a histone deacetylase inhibitor that displays anticancer activity. It inhibits cell proliferation, invasion and migration and induces apoptosis in glioma cells. It also inhibits protein isoprenylation, depletes plasma glutamine, increases production of foetal haemoglobin through transcriptional activation of the gamma-globin gene and affects hPPARgamma activation.
Molecular Spectra
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References
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