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ID:182152
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ID:105675
SQ 22,536
Sigma Aldrich
ID: S153
Names and Identifiers
Synonyms
9-(Tetrahydro-2-furanyl)-9H-purin-6-amine
SQ 22,536
9-THF-Ade
IUPAC Traditional name
9-(oxolan-2-yl)purin-6-amine
IUPAC name
9-(oxolan-2-yl)-9H-purin-6-amine
Registration numbers
CAS Number
17318-31-9
PubChem SID
24278057
MDL Number
MFCD00210216
Properties
Safety Information
GHS Signal Word
Warning
Safety Statements
26
-
36
German water hazard class
3
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
GHS Precautionary statements
P261
-
P305+P351+P338
Risk Statements
36/37/38
GHS Pictograms
Acute toxicity (oral, dermal, inhalation), category 4
Skin irritation, category 2
Eye irritation, category 2
Skin sensitisation, category 1
Specific Target Organ Toxicity – Single exposure, category 3
GHS Hazard statements
H315
-
H319
-
H335
European Hazard Symbols
Irritant (Xi)
Physical Property
Solubility
DMSO: >10 mg/mL
H2O: >10 mg/mL
Apperance
white to off-white powder
Pharmacology Properties
Gene Information
human ... ADCY1(107), ADCY2(108), ADCY3(109), ADCY4(196883), ADCY5(111), ADCY6(112), ADCY7(113), ADCY8(114), ADCY9(115)rat ... Adora1(29290), Adora2a(25369)
Product Information
Purity
≥97% (HPLC)
Molecule Details
Biochem/physiol Actions
SQ 22,536 is a cell-permeable adenylyl cyclase inhibitor. IC50 = 20 μM in detergent-dispersed rat brain preparation.
Molecular Spectra
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References
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