Substance
ID:182118
Names and Identifiers
IUPAC name
N-[2-(5-hydroxy-1H-indol-3-yl)ethyl]acetamide
Synonyms
N-AcetylserotoninN-Acetyl-5-hydroxytryptamineNormelatonin
IUPAC Traditional name
N-acetylserotonin
Properties
Physical Property
Melting Point
120-122 °C(lit.)
Apperance
white powder
Solubility
ethanol: soluble50 mg/mL
Product Information
Purity
≥99% (TLC)
Pharmacology Properties
Gene Information
human ... MTNR1A(4543), MTNR1B(4544)
Safety Information
Storage Temperature
2-8°C
German water hazard class
3
Personal Protective Equipment
Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Molecule Details
包装
1 g in poly bottle
100, 250 mg in poly bottle
Biochem/physiol Actions
Immediate precursor of melatonin. It is formed from serotonin and acetyl-CoA in a reaction catalyzed by serotonin N-acetyl transferase, the rate-limiting enzyme in melatonin biosynthesis. This indoleamine is a weak agonist at melatonin receptors, and has moderate effects on G-protein stimulation and inhibition of cAMP accumulation.
1 g in poly bottle
100, 250 mg in poly bottle
Biochem/physiol Actions
Immediate precursor of melatonin. It is formed from serotonin and acetyl-CoA in a reaction catalyzed by serotonin N-acetyl transferase, the rate-limiting enzyme in melatonin biosynthesis. This indoleamine is a weak agonist at melatonin receptors, and has moderate effects on G-protein stimulation and inhibition of cAMP accumulation.
Molecular Spectra
No Data Available
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References
No Data Available
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