Substance
ID:182090
Names and Identifiers
IUPAC Traditional name
3-[3-(4,4-diphenylpiperidin-1-yl)propyl] 5-methyl (4S)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate hydrochloride
IUPAC name
3-[3-(4,4-diphenylpiperidin-1-yl)propyl] 5-methyl (4S)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate hydrochloride
Synonyms
S(+)-1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid 3-(4,4-diphenyl-1-piperidinyl)-propyl methyl ester hydrochlorideS(+)-Niguldipine hydrochloride
Properties
Physical Property
Solubility
DMSO: soluble13 mg/mL
H2O: insoluble
ethanol: soluble16 mg/mL
dilute aqueous acid: insoluble
methanol: soluble8 mg/mL
Apperance
yellow solid
Optical Rotation
[α]22/D +14.62°, c = 0.13 in methanol(lit.)
Safety Information
Storage Temperature
-20°C
German water hazard class
3
Personal Protective Equipment
Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Molecule Details
Caution
Photosensitive. This compound adsorbs strongly to plastic.
Biochem/physiol Actions
α1A-adrenoceptor antagonist; antihypertensive agent; L-type Ca2+ channel blocker; potassium agonist that activates Ca2+-activated maxi K-channels.
Photosensitive. This compound adsorbs strongly to plastic.
Biochem/physiol Actions
α1A-adrenoceptor antagonist; antihypertensive agent; L-type Ca2+ channel blocker; potassium agonist that activates Ca2+-activated maxi K-channels.
Molecular Spectra
No Data Available
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References
No Data Available
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