Substance
ID:182079
Names and Identifiers
IUPAC name
2-[1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]acetic acid
Synonyms
1-(4-氯苯甲酰基)-5-甲氧基-2-甲基-3-吲哚乙酸Indomethacin吲哚美辛
IUPAC Traditional name
indomethacin
Registration numbers
CAS Number
MDL Number
EC Number
Beilstein Number
PubChem SID
Properties
Product Information
Purity
≥99% (TLC)
Safety Information
UN Number
2811
GHS Pictograms
Acute toxicity (oral, dermal, inhalation), categories 1,2,3
GHS Hazard statements
H300
GHS Precautionary statements
P264-P301+P310
Risk Statements
28
German water hazard class
3
Hazard Class
6.1
GHS Signal Word
Danger
Personal Protective Equipment
Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
RTECS
NL3500000
European Hazard Symbols
Highly toxic (T+)RID/ADR
UN 2811 6.1/PG 1
Packing Group
1
Safety Statements
28-36/37-45
Pharmacology Properties
Gene Information
human ... ALB(213), ALOX5(240), ELA2(1991), GPR44(11251), IL1A(3552), PLA2G1B(5319), PTGDR(5729), PTGS1(5742), PTGS2(5743)mouse ... Alox5(11689), Ptgdr(19214), Ptger1(19216), Ptger2(19217), Ptger3(19218), Ptger4(19219), Ptgs1(19224)rat ... Alox5(25290), Ptgs1(24693), Ptgs2(29527)
Molecule Details
Biochem/physiol Actions
环加氧酶 (COX) 抑制剂，对 COX-1 的选择性相对较高。
环加氧酶 (COX) 抑制剂，对 COX-1 的选择性相对较高。
Molecular Spectra
No Data Available
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References
No Data Available
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