Substance
ID:1820657
Names and Identifiers
IUPAC Traditional name
hydrocortisone
IUPAC name
(1R,3aS,3bS,9aR,9bS,10S,11aS)-1,10-dihydroxy-1-(2-hydroxyacetyl)-9a,11a-dimethyl-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-7-one
Synonyms
cortisol(11beta)-11,17,21-trihydroxypregn-4-ene-3,20-dione11beta,17alpha,21-Trihydroxy-4-pregnene-3,20-dione11beta,17alpha,21-trihydroxy-4-pregnene-3,20-dione11beta-hydrocortisone17-hydroxycorticosterone4-pregnen-11beta,17alpha,21-triol-3,20-dioneCortisolHydrocortisoneKendall's compound FReichstein's substance Mcortisol
International Nonproprietary Name (INN)
hidrocortisonahydrocortisonehydrocortisonum
Registration numbers
CAS Number
Beilstein Number
PubChem CID
DrugBank ID
KEGG ID
LINCS Database
LIPID MAPS Instance
BRENDA Database
CHEMBL
CompTox Database
MetaboLights Database
MTBLS4463MTBLS4820MTBLS656MTBLS612MTBLS2267MTBLS93MTBLS690MTBLS4012MTBLS2291MTBLS2394MTBLS1051MTBLS2579MTBLS124MTBLS136MTBLS1785MTBLS1757MTBLS205MTBLS204MTBLS3056MTBLS292MTBLS3627MTBLS3628MTBLS3935MTBLS417MTBLS407MTBLS3854MTBLS2096MTBLS1906MTBLS1918MTBLS220MTBLS2224MTBLS2776MTBLS2772MTBLS2633MTBLS1693MTBLS2145
SureChEMBL Database
UniProt Database
Q8TCY5Q9JM04P49888Q01718P26439Q5JWF2P63092O70513P68000P68001P01190P19402P01189P21252P01201P01193P11280P01192P06297P01194P01191P15428Q13423O95479O77667P80365P51661P51976Q6R0J2P50172Q6PQJ9P08185O60806Q9MYW9Q9TTR7Q90733P24468P43135O09018P21956P31214P05093Q9IAC6P79404P22199Q4JM28Q9N0W8Q9BDJ7Q29131Q91573Q3YC04Q8QHI2P08235Q8VII8P84996Q9STX2P04150P15538P28549Q13601O95467O00170P50233P50168Q6QLL4P28845Q7M3I4Q29608P08686
IntEnz Database
PDBeChem Database
Wikipedia Title
VirtualMetabolicHuman Database
Patent number
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
BioModels Database
GeneOntology Database
Drug Central Database
BindingDB Database
KEGG DRUG Database
Reactom Database
ArrayExpress (Gene Expression Altlas)
NURSA Database
PubChem SID
Properties
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Molecule Details
A 17alpha-hydroxy-C21-steroid that is pregn-4-ene substituted by oxo groups at positions 3 and 20 and hydroxy groups at positions 11, 17 and 21. Cortisol is a corticosteroid hormone or glucocorticoid produced by zona fasciculata of the adrenal cortex, which is a part of the adrenal gland. It is usually referred to as the "stress hormone" as it is involved in response to stress and anxiety, controlled by corticotropin-releasing hormone (CRH). It increases blood pressure and blood sugar, and reduces immune responses
Molecular Spectra
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References
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