Substance
ID:181986
Names and Identifiers
IUPAC Traditional name
3-{1-[2-(3,4-dichlorophenyl)-N-methylacetamido]-2-(pyrrolidin-1-yl)ethyl}phenoxyacetic acid hydrochloride
IUPAC name
2-(3-{1-[2-(3,4-dichlorophenyl)-N-methylacetamido]-2-(pyrrolidin-1-yl)ethyl}phenoxy)acetic acid hydrochloride
Synonyms
(±)-1-[2,3-(Dihydro-7-methyl-1H-inden-4-yl)oxy]-3-[(1-methylethyl)amino]-2-butanol hydrochlorideR,S-[3-[1-[[(3,4-Dichlorophenyl)acetyl]methylamino]-2-(1-pyrrolidinyl)ethyl] phenoxy]-acetic acid hydrochlorideICI 204,448 hydrochloride
Properties
Physical Property
Solubility
H2O: soluble4.5 mg/mL
45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: soluble12 mg/mL
dilute sodium carbonate: soluble4 mg/mL
Apperance
white solid
Safety Information
Personal Protective Equipment
Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
German water hazard class
3
Pharmacology Properties
Gene Information
human ... OPRK1(4986)
Molecule Details
Biochem/physiol Actions
κ opioid receptor agonist that does not cross the blood-brain barrier.
κ opioid receptor agonist that does not cross the blood-brain barrier.
Molecular Spectra
No Data Available
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References
No Data Available
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