Substance
ID:181918
Names and Identifiers
IUPAC name
N-[2-(5-methoxy-1H-indol-3-yl)ethyl]acetamide
IUPAC Traditional name
melatonin
Synonyms
N-乙酰基-5-甲氧基色胺褪黑素Melatonin
Registration numbers
CAS Number
Beilstein Number
MDL Number
EC Number
PubChem SID
Properties
Physical Property
Apperance
off-white powder
Melting Point
116.5-118 °C(lit.)
Solubility
H2O: soluble0.1 mg/mL
ethanol: soluble8 mg/mL
Safety Information
RTECS
AC5955000
Personal Protective Equipment
Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Storage Temperature
-20°C
German water hazard class
2
Product Information
Purity
≥98% (TLC)
Pharmacology Properties
Gene Information
human ... MTNR1A(4543), MTNR1B(4544), NOS1(4842), NOS2(4843), NOS2B(201288), NOS2C(645740), NOS3(4846)
Molecule Details
Caution
Solutions are light sensitive and subject to oxidation.
包装
1, 5, 10 g in glass bottle
250 mg in glass bottle
Biochem/physiol Actions
Hormone; mediates photoperiodicity in mammals; inhibits cerebellar nitric oxide synthetase; peroxynitrite scavenger. Melatonin has complex effects on apoptotic pathways, inhibiting apoptosis in immune cells and neurons but enhancing apoptotic cell death of cancer cells. Inhibits proliferation/metastasis of breast cancer cells by inhibiting estrogen receptor action.
Other Notes
Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. M5250.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.
Solutions are light sensitive and subject to oxidation.
包装
1, 5, 10 g in glass bottle
250 mg in glass bottle
Biochem/physiol Actions
Hormone; mediates photoperiodicity in mammals; inhibits cerebellar nitric oxide synthetase; peroxynitrite scavenger. Melatonin has complex effects on apoptotic pathways, inhibiting apoptosis in immune cells and neurons but enhancing apoptotic cell death of cancer cells. Inhibits proliferation/metastasis of breast cancer cells by inhibiting estrogen receptor action.
Other Notes
Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. M5250.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.
Molecular Spectra
No Data Available
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References
No Data Available
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