Substance
ID:181875
Names and Identifiers
IUPAC name
6-[4-(difluoromethoxy)-3-methoxyphenyl]-2,3-dihydropyridazin-3-one
Synonyms
Zardaverine6-(4-Difluoromethoxy-3-methoxyphenyl)-3(2H)-pyridazinone
IUPAC Traditional name
zardaverine
Properties
Safety Information
Personal Protective Equipment
Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
German water hazard class
3
Product Information
Potency
2.5 μM IC50 (for PDE III)
1.1 μM IC50 (for PDE IV)
Pharmacology Properties
Gene Information
human ... PDE3A(5139), PDE3B(5140), PDE4A(5141), PDE4B(5142), PDE4C(5143), PDE4D(5144), PDE5A(8654), PDE7A(5150)rat ... Pde2a(81743), Pde4a(25638)
Molecule Details
Biochem/physiol Actions
Selective inhibitor of phosphodiesterase III/IV (PDE3/4).1
Selective inhibitor of phosphodiesterase III/IV (PDE3/4).1
Molecular Spectra
No Data Available
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References
No Data Available
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