Substance
ID:181847
Names and Identifiers
IUPAC Traditional name
(3S)-3-[(2S)-2-[(2S)-2-{[(benzyloxy)carbonyl]amino}-3-methylbutanamido]propanamido]-5-fluoro-4-oxopentanoic acid
IUPAC name
(3S)-3-[(2S)-2-[(2S)-2-{[(benzyloxy)carbonyl]amino}-3-methylbutanamido]propanamido]-5-fluoro-4-oxopentanoic acid
Synonyms
Z-VAD-FMK, Non-methylatedZ-Val-Ala-Asp fluoromethyl ketone
Registration numbers
MDL Number
Properties
Physical Property
Apperance
powder
Product Information
Shipped in
dry ice
Purity
≥90% (TLC)
Safety Information
Personal Protective Equipment
Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
German water hazard class
3
Storage Temperature
-20°C
Molecule Details
Amino Acid Sequence
Z-Val-Ala-Asp-OMe-FMK
Biochem/physiol Actions
Non-methylated competitive and irreversible inhibitor of caspase-1, as well as other caspases, which can be used directly with purified enzymes. It does not require esterase to hydrolyze the O-methyl ester like the cell-permeable form, Z-Val-Ala-Asp(OMe) fluoromethyl ketone (Product Code V-116).
Z-Val-Ala-Asp-OMe-FMK
Biochem/physiol Actions
Non-methylated competitive and irreversible inhibitor of caspase-1, as well as other caspases, which can be used directly with purified enzymes. It does not require esterase to hydrolyze the O-methyl ester like the cell-permeable form, Z-Val-Ala-Asp(OMe) fluoromethyl ketone (Product Code V-116).
Molecular Spectra
No Data Available
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References
No Data Available
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