Substance

ID:181831

Names and Identifiers
IUPAC name
4-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2-dihydro-1,3,5-triazin-2-one
IUPAC Traditional name
azacitidine
Synonyms
5-氮杂胞嘧啶核苷阿扎胞苷5-Azacytidine4-氨基-1-(β-D-呋喃核糖基)-1,3,5-三嗪-2(1H)-酮
Registration numbers
Beilstein Number
CAS Number
PubChem SID
MDL Number
EC Number
Properties
Product Information
Impurities
endotoxin, tested
Suitability
suitable for hybridoma
Grade
Hybri-Max™
Sterility
γ-irradiated
Physical Property
Apperance
lyophilized powder
Melting Point
226-232 °C (dec.)(lit.)
Safety Information
European Hazard Symbols
Toxic Toxic (T)
Risk Statements
45-46-22
GHS Signal Word
Danger
GHS Precautionary statements
P201-P308+P313
RTECS
XZ3017500
GHS Pictograms
GHS07
Acute toxicity (oral, dermal, inhalation), category 4
Skin irritation, category 2
Eye irritation, category 2
Skin sensitisation, category 1
Specific Target Organ Toxicity – Single exposure, category 3
GHS08
Respiratory sensitization, category 1
Germ cell mutagenicity, categories 1A,1B,2
Carcinogenicity, categories 1A,1B,2
Reproductive toxicity, categories 1A,1B,2
Specific Target Organ Toxicity – Single exposure, categories 1,2
Specific Target Organ Toxicity – Repeated exposure, categories 1,2
Aspiration Hazard, category 1
Personal Protective Equipment
Eyeshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
German water hazard class
3
GHS Hazard statements
H302-H350
Safety Statements
22-36/37/39-45
Storage Temperature
-20°C
Molecule Details
Frequently Asked Questions
Live Chat and Frequently Asked Questions are available for this Product.
Application
Used to study the effects of the DNA incorporated molecule on DNA methylation processes.
Reconstitution
10mL 无菌细胞培养基可复原一小瓶本品。储备液足以制备 500mL 培养基。最终工作浓度:10μM 5-氮杂胞嘧啶核苷。
Biochem/physiol Actions
一种强效生长抑制剂及细胞毒素剂,抑制 DNA 甲基转移酶,一种基因表达、基因激活和沉默的重要调节机制。
法律信息
Hybri-Max 商标 Sigma-Aldrich Co. LLC
Molecular Spectra
No Data Available
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References
No Data Available
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