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Substance
ID:181665
Structure
Similarity
Functional Group
Text
ID:132885
(±)-AMPA
Sigma Aldrich
ID: A6816
Names and Identifiers
IUPAC Traditional name
AMPA hydrate
IUPAC name
2-amino-3-(3-hydroxy-5-methyl-1,2-oxazol-4-yl)propanoic acid hydrate
Synonyms
(±)-α-Amino-3-hydroxy-5-methylisoxazole-4-propionic acid hydrate
(±)-AMPA
Registration numbers
PubChem SID
24891141
CAS Number
74341-63-2
MDL Number
MFCD00213388
Properties
Physical Property
Apperance
white solid
Solubility
DMSO: soluble4.3 mg/mL
0.1 M HCl: soluble3.5 mg/mL
1 M HCl: soluble50 mg/mL
H2O: soluble1 mg/mL (warm)
0.1 M NaOH: soluble4.3 mg/mL
Pharmacology Properties
Gene Information
rat ... Gria1(50592), Gria2(29627), Gria3(29628), Gria4(29629), Grik1(29559), Grik2(54257), Grin2a(24409), Grm1(24414), Grm2(24415), Grm4(24417), Grm5(24418), Slc1a1(25550), Slc1a2(29482), Slc1a3(29483)
Safety Information
German water hazard class
3
Personal Protective Equipment
Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Molecule Details
Biochem/physiol Actions
Potent excitatory amino acid that interacts selectively with central AMPA/kainate receptors.
Molecular Spectra
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References
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