Substance
ID:181649
Names and Identifiers
IUPAC name
2-amino-2-(hydroxymethyl)propane-1,3-diol; 5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid
Synonyms
Toradol(±)-5-Benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid tris saltKetorolac tris salt
IUPAC Traditional name
ketorolac; tris buffer
Properties
Safety Information
GHS Signal Word
Danger
Personal Protective Equipment
Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
Safety Statements
26-45
UN Number
2811
GHS Pictograms
Acute toxicity (oral, dermal, inhalation), categories 1,2,3
European Hazard Symbols
Toxic (T)RTECS
UY7759900
German water hazard class
3
RID/ADR
UN 2811 6.1/PG 3
GHS Precautionary statements
P261-P301+P310-P305+P351+P338
Packing Group
3
Risk Statements
25-36/37/38
GHS Hazard statements
H301-H315-H319-H335
Hazard Class
6.1
Physical Property
Apperance
crystalline
Solubility
H2O: soluble15 mg/mL (stable at least one month at -20 °C.)
Product Information
Purity
≥99%
Pharmacology Properties
Gene Information
human ... PTGS1(5742)
Molecule Details
Biochem/physiol Actions
Non-steroidal anti-inflammatory agent and cyclooxygenase (COX) inhibitor that is relatively selective for COX-1. Inhibits the induction of nitric oxide synthase by lipopolysaccharide in a murine macrophage cell line. Part of its analgesic effect may be due to the release of opioid peptides.
Caution
Stable at least 2 years if stored at room temperature.
Non-steroidal anti-inflammatory agent and cyclooxygenase (COX) inhibitor that is relatively selective for COX-1. Inhibits the induction of nitric oxide synthase by lipopolysaccharide in a murine macrophage cell line. Part of its analgesic effect may be due to the release of opioid peptides.
Caution
Stable at least 2 years if stored at room temperature.
Molecular Spectra
No Data Available
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References
No Data Available
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