Substance
ID:181640
Names and Identifiers
Synonyms
1,4,5,6-Tetrahydro-1-methyl-2-(2-[3-methyl-2-thienyl]ethenyl)pyrimidineMorantel citrate salt
IUPAC name
1-methyl-2-[(E)-2-(3-methylthiophen-2-yl)ethenyl]-1,4,5,6-tetrahydropyrimidine; 2-hydroxypropane-1,2,3-tricarboxylic acid
IUPAC Traditional name
citro; morantel
Properties
Safety Information
European Hazard Symbols
Harmful (Xn)German water hazard class
3
GHS Precautionary statements
P280
Risk Statements
20/21/22
Safety Statements
36
GHS Pictograms
Acute toxicity (oral, dermal, inhalation), category 4
Skin irritation, category 2
Eye irritation, category 2
Skin sensitisation, category 1
Specific Target Organ Toxicity – Single exposure, category 3
GHS Signal Word
Warning
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
GHS Hazard statements
H302-H312-H332
Molecule Details
Application
Morantel is a anthelmintic compound used to treat parasitic infections in livestock1. It is also used to study allosteric potentiation of rat neuronal nicotinic acetylcholine receptors (nAChRs)1 and is used to study nematode nicotinic receptors2.
Biochem/physiol Actions
Morantel is a potent non-canonical (binding site) acetylcholine (ACh) receptor agonist and inhibits fumarate reductase. Morantel increases the macroscopic currents evoked by acetylcholine (ACh) from nAChRs expressed in Xenopus laevis oocytes up to 8 times1.
Morantel is a potent non-canonical (binding site) acetylcholine (ACh) receptor agonist and inhibits fumarate reductase.
Morantel is a anthelmintic compound used to treat parasitic infections in livestock1. It is also used to study allosteric potentiation of rat neuronal nicotinic acetylcholine receptors (nAChRs)1 and is used to study nematode nicotinic receptors2.
Biochem/physiol Actions
Morantel is a potent non-canonical (binding site) acetylcholine (ACh) receptor agonist and inhibits fumarate reductase. Morantel increases the macroscopic currents evoked by acetylcholine (ACh) from nAChRs expressed in Xenopus laevis oocytes up to 8 times1.
Morantel is a potent non-canonical (binding site) acetylcholine (ACh) receptor agonist and inhibits fumarate reductase.
Molecular Spectra
No Data Available
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References
No Data Available
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