Substance
ID:181630
Names and Identifiers
IUPAC name
2-phenyl-2,3-dihydro-1,2-benzoselenazol-3-one
IUPAC Traditional name
ebselen
Synonyms
2-Phenyl-1,2-benzisoselenazol-3(2H)-oneEbselen
Properties
Safety Information
German water hazard class
3
GHS Signal Word
Danger
Risk Statements
23/25-33-50/53
Hazard Class
6.1
GHS Pictograms
Hazardous to the aquatic environment
Acute hazard, category1
Chronic hazard, categories 1,2
Respiratory sensitization, category 1
Germ cell mutagenicity, categories 1A,1B,2
Carcinogenicity, categories 1A,1B,2
Reproductive toxicity, categories 1A,1B,2
Specific Target Organ Toxicity – Single exposure, categories 1,2
Specific Target Organ Toxicity – Repeated exposure, categories 1,2
Aspiration Hazard, category 1
Acute toxicity (oral, dermal, inhalation), categories 1,2,3
Packing Group
3
GHS Precautionary statements
P261-P273-P301+P310-P311-P501
European Hazard Symbols
Nature polluting (N)
Toxic (T)Safety Statements
20/21-28-45-60-61
UN Number
3283
RID/ADR
UN 3283 6.1/PG 3
GHS Hazard statements
H301-H331-H373-H410
Storage Temperature
2-8°C
Molecule Details
Biochem/physiol Actions
An organo-selenium compound possessing antioxidant properties. Inhibits mammalian lipoxygenases in the absence of thiol groups, and glutathione S-transferase and papain via the interaction with cysteine residues. Also inhibits indoleamine 2,3-dioxygenase by covalently modifying a cysteine residue, the effect being reversible with dithiothreitol.1 Inhibits oxidation of low density lipoproteins (LDL).
An organo-selenium compound possessing antioxidant properties. Inhibits mammalian lipoxygenases in the absence of thiol groups, and glutathione S-transferase and papain via the interaction with cysteine residues. Also inhibits indoleamine 2,3-dioxygenase by covalently modifying a cysteine residue, the effect being reversible with dithiothreitol.1 Inhibits oxidation of low density lipoproteins (LDL).
Molecular Spectra
No Data Available
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References
No Data Available
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