Substance
ID:181579
Names and Identifiers
Synonyms
17-(Cyclobutylmethyl)-4,5-epoxymorphinan-3,6,14-triol hydrochloride hydrateNalbuphine hydrochloride hydrate
IUPAC name
(1S,5R,13R,14S,17S)-4-(cyclobutylmethyl)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-triene-10,14,17-triol hydrate hydrochloride
IUPAC Traditional name
nalbuphine hydrate hydrochloride
Properties
Physical Property
Solubility
ethanol: soluble
H2O: soluble
Safety Information
GHS Signal Word
Danger
Drug Control
regulated under CDSA - not available from Sigma-Aldrich Canada
GHS Pictograms
Acute toxicity (oral, dermal, inhalation), categories 1,2,3
Safety Statements
22-36/37/39-45
Hazard Class
6.1
RID/ADR
UN 2811 6.1/PG 2
European Hazard Symbols
Highly toxic (T+)Personal Protective Equipment
Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
Packing Group
2
German water hazard class
3
GHS Hazard statements
H300-H310-H330
GHS Precautionary statements
P260-P264-P280-P284-P302+P350-P310
Risk Statements
26/27/28
RTECS
QD3181000
UN Number
2811
Product Information
Purity
≥98% (HPLC)
Pharmacology Properties
Gene Information
human ... OPRK1(4986), OPRM1(4988)
Molecule Details
Biochem/physiol Actions
Partial agonist for μ and κ opioid receptors.
Partial agonist for μ and κ opioid receptors.
Molecular Spectra
No Data Available
Click here to submit data
References
No Data Available
Click here to submit data