Substance
ID:181560
Names and Identifiers
IUPAC Traditional name
baclofen
IUPAC name
4-amino-3-(4-chlorophenyl)butanoic acid
Synonyms
Lioresal(±)-Baclofen(±)-β-(Aminomethyl)-4-chlorobenzenepropanoic acid
Properties
Safety Information
GHS Signal Word
Danger
Risk Statements
61-25-36/37/38-42/43
RTECS
MW5084200
GHS Pictograms
Acute toxicity (oral, dermal, inhalation), categories 1,2,3
Respiratory sensitization, category 1
Germ cell mutagenicity, categories 1A,1B,2
Carcinogenicity, categories 1A,1B,2
Reproductive toxicity, categories 1A,1B,2
Specific Target Organ Toxicity – Single exposure, categories 1,2
Specific Target Organ Toxicity – Repeated exposure, categories 1,2
Aspiration Hazard, category 1
Storage Temperature
2-8°C
UN Number
2811
RID/ADR
UN 2811 6.1/PG 3
Safety Statements
53-22-36/37/39-45
GHS Precautionary statements
P201-P261-P280-P301+P310-P305+P351+P338-P308+P313
Hazard Class
6.1
German water hazard class
3
Packing Group
3
GHS Hazard statements
H301-H315-H317-H319-H334-H335-H360
European Hazard Symbols
Toxic (T)Personal Protective Equipment
Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
Physical Property
Apperance
white to very faintly yellow solid
Solubility
1 M HCl: soluble50 mg/mL
Pharmacology Properties
Gene Information
human ... GABBR1(2550), GABBR2(9568)rat ... Gabbr1(81657), Gabra2(29706)
Product Information
Purity
≥98% (TLC)
Molecule Details
Biochem/physiol Actions
GABAB receptor agonist; skeletal muscle relaxant; antispastic agent.
GABAB receptor agonist; skeletal muscle relaxant; antispastic agent.
Molecular Spectra
No Data Available
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References
No Data Available
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