Substance
ID:181474
Names and Identifiers
IUPAC name
N-(4-{1-hydroxy-2-[(propan-2-yl)amino]ethyl}phenyl)methanesulfonamide hydrochloride
IUPAC Traditional name
sotalol hydrochloride
Synonyms
N-[4-[1-Hydroxy-2-(isopropylamino)ethyl]phenyl]methanesulfonamide hydrochloride(±)-Sotalol hydrochloride
Properties
Safety Information
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
GHS Hazard statements
H315-H319-H335
European Hazard Symbols
Irritant (Xi)GHS Precautionary statements
P261-P305+P351+P338
GHS Pictograms
Acute toxicity (oral, dermal, inhalation), category 4
Skin irritation, category 2
Eye irritation, category 2
Skin sensitisation, category 1
Specific Target Organ Toxicity – Single exposure, category 3
GHS Signal Word
Warning
Risk Statements
36/37/38
RTECS
PB0826000
Safety Statements
26-36
German water hazard class
3
Physical Property
Apperance
white to off-white powder
Solubility
H2O: soluble20 mg/mL
Product Information
Purity
≥98% (TLC)
Pharmacology Properties
Gene Information
human ... ADRB1(153), ADRB2(154), ADRB3(155)
Molecule Details
Biochem/physiol Actions
Potent β-adrenoceptor antagonist; class III antiarrhythmic; prolongs the action potential and increases the refractory period.
Potent β-adrenoceptor antagonist; class III antiarrhythmic; prolongs the action potential and increases the refractory period.
Molecular Spectra
No Data Available
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References
No Data Available
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