Substance
ID:181374
Names and Identifiers
Synonyms
Ketanserin (+)-tartrate salt3-(2-[4-(4-Fluorobenzoyl)-1-piperidinyl]ethyl)-2,4(1H,3H)-quinazolinedione (+)-tartrate saltR 41468 (+)-tartrate salt
IUPAC name
(2R,3R)-2,3-dihydroxybutanedioic acid; 3-{2-[4-(4-fluorobenzoyl)piperidin-1-yl]ethyl}-1,2,3,4-tetrahydroquinazoline-2,4-dione
IUPAC Traditional name
L(+)-tartaric acid; ketanserin
Properties
Product Information
Purity
≥97%
Physical Property
Solubility
DMSO: soluble52 mg/mL
0.1 M HCl: soluble6 mg/mL
ethanol: soluble3.3 mg/mL
Apperance
white solid
Safety Information
European Hazard Symbols
Toxic (T)Risk Statements
25
GHS Precautionary statements
P301+P310
RID/ADR
UN 2811 6.1/PG 3
Packing Group
3
GHS Signal Word
Danger
German water hazard class
3
RTECS
VA1411195
Safety Statements
22-36/37/39-45
GHS Pictograms
Acute toxicity (oral, dermal, inhalation), categories 1,2,3
Personal Protective Equipment
Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
Storage Temperature
2-8°C
Hazard Class
6.1
UN Number
2811
GHS Hazard statements
H301
Pharmacology Properties
Gene Information
human ... HTR2A(3356), HTR2B(3357), HTR2C(3358)
Molecule Details
Biochem/physiol Actions
Selective 5-HT2 serotonin receptor antagonist. Ketanserin significantly reduces nicotine self-administration in rats, supporting an unexpected involvement of serotonin in nicotine addiction.1
Selective 5-HT2 serotonin receptor antagonist. Ketanserin significantly reduces nicotine self-administration in rats, supporting an unexpected involvement of serotonin in nicotine addiction.1
Molecular Spectra
No Data Available
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References
No Data Available
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