Substance
ID:181166
Names and Identifiers
IUPAC Traditional name
amphotericin B
Synonyms
FungizoneAmphotericin B solubilized
IUPAC name
(1R,3S,5R,6R,9R,11R,15S,16R,17R,18S,19Z,21Z,23Z,25Z,27Z,29Z,31Z,33R,35S,36R,37S)-33-{[(2R,3S,4S,5S,6R)-4-amino-3,5-dihydroxy-6-methyloxan-2-yl]oxy}-1,3,5,6,9,11,17,37-octahydroxy-15,16,18-trimethyl-13-oxo-14,39-dioxabicyclo[33.3.1]nonatriaconta-19,21,23,25,27,29,31-heptaene-36-carboxylic acid
Registration numbers
Beilstein Number
CAS Number
MDL Number
PubChem SID
Properties
Safety Information
German water hazard class
3
Safety Statements
26
Storage Temperature
2-8°C
GHS Pictograms
Acute toxicity (oral, dermal, inhalation), category 4
Skin irritation, category 2
Eye irritation, category 2
Skin sensitisation, category 1
Specific Target Organ Toxicity – Single exposure, category 3
GHS Signal Word
Warning
European Hazard Symbols
Harmful (Xn)GHS Precautionary statements
P261-P305+P351+P338
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Risk Statements
22-36/37/38
GHS Hazard statements
H315-H319-H335
Product Information
Sterility
γ-irradiated
Suitability
suitable for cell culture
Quality Level
PREMIUM
Physical Property
Solubility
sterile water: soluble20 mg/mL (as a stock solution. Stock solutions should be stored at -20 °C. Stable at 37 °C for 3 days.)
Apperance
powder
Molecule Details
Frequently Asked Questions
Live Chat and Frequently Asked Questions are available for this Product.
Application
Recommended for use in cell culture applications at 5.6 mg (solid)/L. It is used to study the formation of ion-permeable channels in fungal cell membranes
Biochem/physiol Actions
Mode of Action: Interferes with fungal membrane permeability by forming channels in the membranes and causing small molecules to leak out.
Polyene antifungal antibiotic from Streptomyces. Affinity for sterols, primarily ergosterols, of fungal cell membranes. Forms channels in the membranes, causing small molecules to leak out. Antimicrobial spectrum: fungi and yeast.
包装
Package size based on amphotericin B
Protocols & Applications
Antibiotic Selector for application, solubility, solution stability, working concentration, and mode of action information
Live Chat and Frequently Asked Questions are available for this Product.
Application
Recommended for use in cell culture applications at 5.6 mg (solid)/L. It is used to study the formation of ion-permeable channels in fungal cell membranes
Biochem/physiol Actions
Mode of Action: Interferes with fungal membrane permeability by forming channels in the membranes and causing small molecules to leak out.
Polyene antifungal antibiotic from Streptomyces. Affinity for sterols, primarily ergosterols, of fungal cell membranes. Forms channels in the membranes, causing small molecules to leak out. Antimicrobial spectrum: fungi and yeast.
包装
Package size based on amphotericin B
Protocols & Applications
Antibiotic Selector for application, solubility, solution stability, working concentration, and mode of action information
Molecular Spectra
No Data Available
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References
No Data Available
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