Substance
ID:180807
Names and Identifiers
IUPAC name
(4E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydro-2-benzofuran-5-yl)-4-methylhex-4-enoic acid
IUPAC Traditional name
mycophenolic acid
Synonyms
6-(1,3-Dihydro-7-hydroxy-5-methoxy-4-methyl-1-oxoisobenzofuran-6-yl)-4-methyl-4-hexanoic acidNSC 129185Mycophenolic acid6-(4-Hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-4-hexenoic acid
Registration numbers
CAS Number
MDL Number
EC Number
Beilstein Number
PubChem SID
Properties
Product Information
Quality Level
PREMIUM
Purity
≥98%
Suitability
suitable for cell culture
Pharmacology Properties
Gene Information
human ... IMPDH1(3614), IMPDH2(3615)
Target Organ
Immune system
Safety Information
GHS Pictograms
Acute toxicity (oral, dermal, inhalation), category 4
Skin irritation, category 2
Eye irritation, category 2
Skin sensitisation, category 1
Specific Target Organ Toxicity – Single exposure, category 3
Respiratory sensitization, category 1
Germ cell mutagenicity, categories 1A,1B,2
Carcinogenicity, categories 1A,1B,2
Reproductive toxicity, categories 1A,1B,2
Specific Target Organ Toxicity – Single exposure, categories 1,2
Specific Target Organ Toxicity – Repeated exposure, categories 1,2
Aspiration Hazard, category 1
Hazardous to the aquatic environment
Acute hazard, category1
Chronic hazard, categories 1,2
GHS Hazard statements
H302-H341-H360D-H372-H410
RTECS
MP8050000
European Hazard Symbols
Nature polluting (N)
Toxic (T)GHS Precautionary statements
P201-P273-P281-P308+P313-P501
GHS Signal Word
Danger
Risk Statements
61-22-48/25-50/53-68
German water hazard class
3
Safety Statements
53-22-45-61
Personal Protective Equipment
Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
Storage Temperature
2-8°C
Physical Property
Solubility
methanol: soluble50 mg/mL
Apperance
powder
Molecule Details
Application
Recommended for use as a selection agent at 25 μg/ml.
Used to select animal cells expressing the Escherichia coli gene for xanthine-guanine phosphosribosyl transferase.
Biochem/physiol Actions
Immunosuppressive agent. Suppresses cytokine-induced nitric oxide production.
Immunosuppressive agent. Used to inhibit early stage biosynthesis of purine nucleotides. Used as a specific inhibitor of inosine 5′-monophosphate (IMP) dehydrogenase (IMPDH) and inducer of IMP dehydrogenase gene expression.
Protocols & Applications
Antibiotic Selector for application, solubility, solution stability, working concentration, and mode of action information
Recommended for use as a selection agent at 25 μg/ml.
Used to select animal cells expressing the Escherichia coli gene for xanthine-guanine phosphosribosyl transferase.
Biochem/physiol Actions
Immunosuppressive agent. Suppresses cytokine-induced nitric oxide production.
Immunosuppressive agent. Used to inhibit early stage biosynthesis of purine nucleotides. Used as a specific inhibitor of inosine 5′-monophosphate (IMP) dehydrogenase (IMPDH) and inducer of IMP dehydrogenase gene expression.
Protocols & Applications
Antibiotic Selector for application, solubility, solution stability, working concentration, and mode of action information
Molecular Spectra
No Data Available
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References
No Data Available
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